8 p.m. ET on ABC Meredith (Ellen Pompeo) finds herself treating a patent who claims to specialize in matchmaking in a new episode called “Gut Feeling.” Meanwhile, another patient, who appears to be drunk, really gets a rise out of Richard (James Pickens Jr.), but also presents him with a legitimate medical puzzle to solve. Elsewhere, Maggie (Kelly McCreary) feels completely overwhelmed by personal issues, so she tries to contact Teddy (Kim Raver). Greg Germann and Chris Carmack guest star.
8 p.m. ET on NBC – Season Premiere
As fans remember, Season 3 ended as will-they-or-won’t-they couple Amy and Jonah (America Ferrera, Ben Feldman) finally did — give in to their passions, that is — not realizing their hook-up was captured by the store’s security cameras. The Season 4 premiere, “Back to School,” opens on their first day back at work after the inevitable suspension that followed, which means they have to prepare themselves for brutal teasing. Elsewhere, Jeff (Michael Bunin) takes extreme measures to win back Mateo (Nico Santos).
8:31 p.m. ET on CBS
Pretty early in its run, “The Big Bang Theory” established that Dr. Sheldon Cooper’s mother was a woman of deep religious convictions, a trait that also has been part of this spinoff and prequel. That aspect of Mary Cooper’s (Zoe Perry) personality comes to the fore in tonight’s new episode “A Crisis of Faith and Octopus Aliens,”which finds Mary’s trust in God badly shaken by a community tragedy, much to the consternation of little Sheldon (Iain Armitage).
9:01 p.m. ET on ABC – Season Premiere
Season 2 of this “Grey’s Anatomy” spinoff picks up the action pretty much where the Season 1 finale left off, with the firefighters battling the raging skyscraper inferno in the premiere, “No Recovery.” Meanwhile, as Pruitt’s (Miguel Sandoval) health continues to be a matter of grave concern at the hospital, a firefighting veteran with a shadowy past arrives at the station, raising several questions for the team. Boris Kodjoe guest stars; Jaina Lee Ortiz and Jason George also star.
9:01 p.m. ET on CBS
Is a relapse — one that has nothing to do with alcohol and drugs — looming in Christy’s (Anna Faris) future? That’s definitely Bonnie’s (Allison Janney) biggest fear when her daughter declares that she feels confident she’s got her past gambling issues under control, so she wants to discontinue her participation in Gamblers Anonymous. Charlie Robinson, Yvette Nicole Brown, Sam McMurray and Susan Ruttan also star in the new episode “Go-Go Boots and a Butt Cushion.”